IT Quiz Answer – Dec 19, 2024

Here is the answer to our weekly Intelligent Thursday quiz!

Emily Morgan, MD
Emily Morgan, MD
4th Dec 2024 • 1m read

Pop Quiz: December 12, 2024

Which of the following medications has an absolute contraindication in older adults?

A. Oral nonsteroidal anti-inflammatory drugs  

B. Oxycodone

C. Tramadol

D. Gabapentin

 

Check your answer!

The correct answer is C. Tramadol

Explanation:

Tramadol is contraindicated in older adults due to its unique mechanism of action, which includes binding to multiple receptors including opiate, adrenergic, and serotonin receptors.

Tramadol is rapidly absorbed and distributed, producing several active metabolites that increase the risk of unpredictable toxicity in older adults.

Oral NSAIDs, oxycodone, and gabapentin may be used in older adults, but with caution.


To learn more about prescribing and deprescribing or reducing polypharmacy in older adults, check out our Geriatric Essentials course linked below.