IT Quiz Answer – October 17, 2024

Answers from our weekly Intelligent Thursday quizzes!

Franz Wiesbauer, MD MPH
Franz Wiesbauer, MD MPH
4th Oct 2024 • 1m read

Pop Quiz: October 17, 2024

Which of the following statements about benzodiazepines is correct?

a. Due to its effects on dopaminergic transmission, diazepam is the most widely misused benzodiazepine.

b. Benzodiazepine intoxication can be managed with IV flumazenil.

c. Benzodiazepine use disorder can be managed with a 5–7 day taper, using a long-acting benzodiazepine.

d. Lorazepam is the most potent benzodiazepine. 

Answer: B

Explanation: 

Benzo intoxication, when complicated by respiratory depression, can be managed with IV flumazenil. 

Alprazolam is the most widely misused benzo, largely due to its modulation of dopaminergic transmission. 

Unlike alcohol use disorder, benzo use disorder requires a prolonged benzo taper, often over the course of 10–12 weeks.

Lastly, milligram for milligram, clonazepam is the most potent benzodiazepine, not Lorazepam.

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